Small airways disease

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Assessing small airways disease.

A simple method of assessing smaller airways obstruction is easily available and could be used retrospectively. In contrast to the mean forced expiratory flow between 25 and 75% of forced vital capacity (FVC; FEF25–75%), which measures the mid-portion of exhalation ending at nearly the same time as the forced expiratory volume in one second (FEV1) in these subjects, the FEV3/FVC% or (1-FEV3/FVC...

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Small airways disease.

Introduction MY subject is 'Disease in the small airways'. I hope no one here today will leave with the mistaken impression that I have been describing some new kind of pulmonary disease. That is not the case. It is my intention first of all to discuss ways in which bronchi may become obstructed and then to consider possible means of investigating obstruction in small airways at a stage when th...

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Imaging of small airways disease.

Small airways disease includes a spectrum of inflammatory and fibrotic pulmonary diseases centered on the small conducting airways. High-resolution computed tomography plays a key role in the detection and classification of small airways disease and, when combined with relevant clinical and pathologic findings, leads to a more accurate diagnosis. The imaging manifestations of small airways dise...

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Small airways disease: time for a revisit?

It is increasingly acknowledged that delays in the diagnosis of chronic inflammatory lung conditions have hampered our understanding of pathogenesis and thus our ability to design efficacious therapies. This is particularly true for COPD, where most patients are diagnosed with moderate-to-severe airflow obstruction and little is known about the inflammatory processes present in early disease. T...

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Multimodality measurements of small airways disease.

S mall airways disease has long been recognised as being physiologically important in obstructive lung diseases, particularly in chronic obstructive pulmonary disease (COPD) [1]. The study of COSIO et al. [2], in which the severity of small airway inflammation and remodelling in smokers correlated with airway closure and ventilation maldistribution, as measured by single breath washout tests, i...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1976

ISSN: 0032-5473

DOI: 10.1136/pgmj.52.606.197